17Q23.2Q23.3 DE NOVO DUPLICATION IN ASSOCIATION WITH SPEECH AND LANGUAGE DISORDER, LEARNING DIFFICULTIES, INCOORDINATION, MOTOR SKILL IMPAIRMENT, AND BEHAVIORAL DISTURBANCES: A CASE REPORT

17q23.2q23.3 de novo duplication in association with speech and language disorder, learning difficulties, incoordination, motor skill impairment, and behavioral disturbances: a case report

Abstract Background Chromosomal rearrangements involving 17q23 have been described rarely.Deletions at 17q23.1q23.2 have been reported in individuals with developmental delay and growth retardation, whereas duplications at 17q23.1q23.2 appear to segregate with clubfoot.Dosage alterations in the TBX2 and TBX4 genes, located in 17q23.2, have been pro

read more

A mixed-methods systematic review protocol to examine the use of physical restraint with critically ill adults and strategies for minimizing their use

Abstract Background Critically ill patients frequently experience severe agitation placing them at risk of harm.Physical restraint is common in intensive care units (ICUs) for clinician concerns about safety.However, physical restraint may not prevent medical device removal and has been associated with negative physical and psychological consequenc

read more


Tusk or Bone? An Example of Ivory Substitute in the Wildlife Trade

Bone carvings (and other ivory substitutes) are common in the modern-day lucrative international ivory trade.Souvenirs for unknowing travelers and market shoppers can be made of non-biological material (plastic "ivory" beads) or refill diffusore ambiente skillfully crafted natural objects made to resemble something other than their true origin.Many

read more